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Your weekly roundup of STAT's First Opinion

 

First Opinion

Midway though the cruellest month, First Opinion authors criticized the word play used to void the travel mask mandate, asked if the shadow of Aduhelm will cloud the FDA's future decisions on new drugs, and more. You can read all of the week's essays here. For podcast fans, the latest episode of the "First Opinion Podcast," on the sorry state of care in many U.S. nursing homes, is live.

In mask mandate case, judge ruled on wordplay, not public health

By Jeffrey E. Harris

PATRICK T. FALLON/AFP via Getty Images

Wordplay should not determine if a federal agency has the authority to take measures to block the transmission of a lethal virus.

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Medicine needs to do right by patients prescribed opioids

By Haider J. Warraich

John Moore/Getty Images

A severe back injury gave one doctor insights into the plight of the 50 million Americans who live with chronic pain.

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Will the shadow of Aduhelm cloud FDA's decision-making on an ALS therapy?

By Bernard Zipprich

Adobe

Amylyx applied for approval of AMX0035, its new drug to treat ALS. Then the FDA's disastrous decision on Aduhelm happened.

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Listen: Covid turned the nation's eyes to nursing homes. Have we already looked away?

By Patrick Skerrett

This week's "First Opinion Podcast" explores the "ineffective" and "inequitable" ways that many nursing homes care for their residents.

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Not going all in on the 988 hotline will ensure its failure

By Benjamin F. Miller

Adobe

Lack of support and funding jeopardizes the rollout of 988, the new nationwide mental health and suicide prevention crisis hotline.

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Men and women may respond differently to vaccines. Research needs to account for that

By Dawn Sinclair Shapiro

Adobe

Vaccine and drug developers need to evaluate sex differences as an integral part of their preclinical and clinical work.

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It's time for Congress to stop blocking mitochondrial replacement therapy

By Walter G. Johnson and Diana M. Bowman

Odra Noel/Wellcome

The budget bill rider that funds the FDA mistakenly shuts down research on mitochondrial replacement, which could benefit some families.

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STAT+: Pharma's role in value-based care starts with value-based research

By Scott Swain and Kristin M. Zimmerman Savill and Bruce Feinberg

Adobe

A value-based care model cannot be generated from traditional trials alone. Something new — value-based research — is needed.

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If there is a digital health bubble, does it really matter for entrepreneurs?

By Alyssa Jaffee

Adobe

It's impossible to say how health care will be affected by the "bubble," if there is one. So companies should keep their eyes on their goals.

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Access to kidney transplantation is improving for everyone, but more work remains to be done

By Richard N. Formica

PIERRE-PHILIPPE MARCOU/AFP/Getty Images

Changes made in how donated kidneys and other organs are allocated has helped improve access to transplants for all people.

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Sunday, April 24, 2022

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