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Moderna says cancer vaccine reduces melanoma’s return; Mirati KRAS-blocking lung cancer drug approved

  

 

Cancer Briefing

Join STAT's Angus Chen and Damian Garde for a virtual discussion tomorrow with industry experts on the most prominent work presented at ASH 2022 and a look at what's coming in hematology in the year ahead. Sign up here.

STAT+: Moderna says cancer vaccine reduces melanoma's return by 44%

By Matthew Herper

Ruby Wallau for STAT

New data offers the first evidence of an effective individualized cancer vaccine based on mRNA, the technology used in the Covid shots.

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STAT+: Mirati wins FDA approval for KRAS-blocking lung cancer drug, but blockbuster sales hopes have dimmed

By Adam Feuerstein

Adobe

Hopes that the Mirati lung cancer drug might reach a large swath of patients — and grow into a commercial blockbuster — have dimmed.

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STAT+: 'We've got a new target': Bispecific antibody for multiple myeloma succeeds in mid-stage trial

By Angus Chen

Adobe

Researchers had hoped that a protein called GPRC5D might offer a new way to get the immune system to hunt and destroy multiple myeloma cells.

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Cancer patients endure an overlooked financial burden: hospital parking fees

By Bob Herman

Adobe

For cancer patients who must make frequent trips for treatments like radiation and chemotherapy, the cost of daily parking fees adds up.

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STAT+: Novartis develops CAR-T therapy that can be made in a fraction of the standard time

By Angus Chen

Ruby Wallau for STAT

The process, which Novartis calls the T-charge platform, cuts the standard 10-day CAR-T cell manufacturing time to less than two days.

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STAT+: Zantac lawsuits are tossed out as judge lambasts lack of evidence showing links to cancer

By Ed Silverman

Drew Angerer/Getty Images

Experts presented "a lack of internally consistent, objective, science-based standards for the evenhanded evaluation of data," the judge wrote

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STAT+: Emerging class of genetically targeted drugs induce remissions in leukemia patients

By Adam Feuerstein

CDC

About one-third of patients with advanced leukemia experienced remissions in two new clinical trials of genetically targeted drugs.

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STAT+: Bone marrow transplant patients could be spared from 'bland' diet, study finds

By Angus Chen

Adobe

“This debunks a myth that we’ve been perpetuating forever,” hematologist Mikkael Sekeres said of the new study presented at the ASH meeting.

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STAT+: Affimed's natural killer cell therapy has murky path forward despite encouraging results

By Adam Feuerstein

NIAID/NIH

An experimental immunotherapy from Affimed has started to demonstrate long-lasting remissions for patients with advanced Hodgkin lymphoma.

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Tuesday, December 13, 2022

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