Breaking News

A mental health crisis in women’s prisons, a new preeclampsia care plan, & unlocking the human genome

April 28, 2023
Good morning! This is Jonathan Wosen, West Coast biotech and life sciences reporter, filling in for Liz today. Here's some news to peruse as you get ready to kick off your weekend.

reproductive Health

Experts issue a detailed care plan for preeclampsia

Roughly 5% to 7% of pregnant people experience preeclampsia, a sharp rise in blood pressure during or after pregnancy that can double a person's chance of later developing heart disease. But while the condition is relatively common, it's one that clinicians and patients can prevent, wrote researchers in a study published today in the American Journal of Obstetrics and Gynecology. 

The study's authors lay out a care plan that revolves around a number of steps, including performing frequent at-home blood pressure checks, eating a Mediterranean diet, and continuing to take needed heart medications that people sometimes avoid when pregnant. These aren't new ideas, writes STAT's Theresa Gaffney, but it's the first time experts have put all of these steps together into a comprehensive plan. Read more.


science

A menagerie of mammals helps scientists unravel human genome's secrets

An underwater image of an Amazon river dolphin
Courtesy Marcos Amend/Pulsar Imagens

Twenty years after the completion of the Human Genome Project, scientists can decode DNA more quickly, accurately, and cheaply than ever before. There's just one problem: We still don't know what most of the genome does. But 11 new studies published in Science are helping researchers unravel the human genome's secrets, with help from an unlikely source — Amazon river dolphins (above), greater mouse-eared bats, and fat-tailed dwarf lemurs.

The studies are part of the Zoonomia project, a massive international effort to compare the genomes of 240 mammalian species. By doing so, scientists can find which DNA sequences have stayed the same across 100 million years of evolution — a telling indicator that a genetic region is important, even if researchers don't yet know its function. Authors found that at least 10.7% of the human genome is functional, a higher estimate than many prior studies. You can read more from yours truly here.


addiction

Pa. lawmakers set to ban supervised drug use sites

Supervised consumption sites, which allow people to use drugs under medical watch, are meant to avoid the worst outcomes of drug use — overdose, death, and disease transmission — while recognizing that, for many people, quitting cold turkey is difficult, if not impossible. But a long-running effort to set up one such site in Philadelphia is now in jeopardy after a committee of state lawmakers endorsed a bill that would outlaw places that "knowingly" provide a space for drug consumption. The state Senate will now vote on the bill. 

If it passes, which is widely expected, the governor, who has openly opposed supervised drug use sites, will likely sign it into law. It's the latest example of a contentious debate around the right way to respond to the country's drug epidemic, STAT's Lev Facher writes, a discussion that has recently taken a rightward turn even in Democratic circles. Read more.



Closer Look

A mental health crisis inside California's women's prisons

An illustration of a cross-section of a prison with women isolated in each cell.
Molly Ferguson for STAT

Pandemic lockdowns weren't easy for anyone, but they took an especially heavy toll on the mental health of those locked up, STAT contributor Taylor Majewski reports, and that has fueled a crisis that continues to this day. For people incarcerated across California's women's prisons, the prison yard and dayroom offer a welcome chance to call family, exercise, and read. But those opportunities were shut off by Covid-19 related lockdowns, cutting off the few freedoms that people had and leaving them locked in their cells for days or weeks.

The result is that many prisoners have felt more trapped, stressed, and hopeless than ever before. And they say these intermittent lockdowns have continued three years later, often with no connection to public health precautions and sometimes without an apparent reason. "It's a standing joke that we can't go 48 hours without some kind of major crisis that locks us down," said Cecilia Fraher, who is incarcerated at the California Institution for Women. Read more.


infectious disease

As temperatures rise, the threat of Zika and dengue will too, study suggests

Many of the world's deadly infectious diseases are spread by the prick of mosquitoes, which thrive in warm climates. And as global temperatures continue to rise, researchers expect viruses such as Zika and dengue to spread even faster. The findings, published yesterday in PLOS Neglected Tropical Diseases, are based on an analysis of historical temperature data from four regions of Brazil and temperature predictions in these regions between 2045 and 2049. 

Scientists project that the reproduction number — the average number of people someone with the virus would infect — could jump as high as 2.7 for Zika and 6.8 for dengue, depending on the temperature. In other words, the study's authors write, these viruses will be more likely to spark epidemics, and it'll be extra important for public health systems to monitor for the earliest signs of transmission.


research

CDC survey of high schoolers highlights growing health concerns

The CDC just released its 2021 Youth Risk Behavior Surveillance, a biennial survey of more than 17,000 U.S. high school students and the first edition of the survey since the pandemic. Some key findings:

  • High schoolers in 2021 were more likely to say they don't eat breakfast daily compared to students in 2019 (75% versus 66.9%, respectively). The percent of students who reported eating less than a serving of fruits and vegetables a day also increased.
  • Physical activity is down. The survey found that while 26% of high schoolers in 2019 reported going to a physical education class each day during a typical school week, that dipped to 19% in 2021.
  • One bright spot: Vaping rates dropped. While roughly half of surveyed students said they had ever used a vaping product in 2019, just 36% of respondents in 2021 said they had done so.

More around STAT
Check out more exclusive coverage with a STAT+ subscription
Read premium in-depth biotech, pharma, policy, and life science coverage and analysis with all of our STAT+ articles.

What we're reading

  • Eli Lilly's Mounjaro succeeds in second weight-loss study, paving way for FDA review, STAT
  • How one patient's textured hair nearly kept her from a needed EEG, KFF Health News
  • Biden officials propose slate of Medicaid transparency changes, STAT
  • Putting radiation to the test to heal irregular heartbeat, Associated Press
  • The meaning of meowing, Wall Street Journal

Thanks for reading. More Monday! — Jonathan

Jonathan Wosen is STAT's West Coast biotech and life sciences reporter.


Enjoying Morning Rounds? Tell us about your experience
Continue reading the latest health & science news with the STAT app
Download on the App Store or get it on Google Play
STAT
STAT, 1 Exchange Place, Boston, MA
©2023, All Rights Reserved.

No comments