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VP Harris on abortion pill access, how much melatonin is really in those gummies, & how transportation barriers put cancer patients at risk

April 26, 2023
Good morning, this is reporter and podcast producer Theresa Gaffney, filling in for Liz. Don't miss Nick Florko's latest dispatch on the commercial determinants of health. This time: Your dosage may vary when it comes to melatonin gummies.

abortion

VP Harris rallies against limits to abortion pill access

At a rally for reproductive rights at her alma mater Howard University last night, Vice President Kamala Harris spanned topics from abortion pill access to gender-affirming care and gun control policies as she urged students to fight back "through votes at the ballot box" — one of the few options left as abortion pill access hangs in appeals court limbo.

After walking onstage to chants of "four more years" (hours after President Biden announced his bid for reelection), Harris repeatedly warned against potential abortion pill limits that could have broad ramifications for FDA authority and spell out a conservative plan for national abortion bans, STAT's Sarah Owermohle reports. "One does not have to abandon their faith or deeply held beliefs to agree the government should not be making this decision," Harris said.


health

Actual dosages in melatonin gummies vary widely

Consumers turning to melatonin gummies for help falling asleep might be getting a lot more than they bargained for, according to a new JAMA study. Researchers tested the melatonin concentration in more than two dozen gummy dietary supplements that were recently launched and available at mainstream retailers like Amazon and Walmart. Nearly all of the products had more than 10% more melatonin than advertised. One product was even three times more powerful than the label suggested. Supplements like melatonin gummies are not subject to FDA review before they're sold.

"This is something that we should be concerned about," Jocelyn Cheng, a senior director at the drugmaker Eisai and a spokesperson for the American Academy of Sleep Medicine, told STAT's Nicholas Florko. "In general [melatonin] is construed as being safe, but in high quantities we just don't have enough data to say with certainty that it would be safe." Read more.


biotech

FDA approves Biogen treatment for rare form of ALS

The FDA granted conditional approval to a new treatment for a rare, genetic form of ALS yesterday — basing its decision on preliminary evidence that may also speed the development of future medicines for the fatal, neurodegenerative disease. It's the first time accelerated approval has been used by the FDA for a medicine to treat ALS.

The new drug, Biogen's Qalsody, is administered by a monthly injection into the spine for people with ALS caused by inherited mutations in a gene called SOD1. Biogen estimates approximately 330 people in the U.S. have this form of ALS, with 120 new cases each year. Qalsody reduces levels of a protein called neurofilament light chain that leaks into the blood and spinal fluid of ALS patients as nerves are damaged. Scientists believe decreases in neurofilament levels will lead to a slowing of neurologic and functional decline in ALS patients, although Biogen will need to confirm the benefit in another clinical trial. The approval comes less than a year after the agency approved another ALS drug from Amylyx last September. STAT's Adam Feuerstein has more.



Closer Look

Students at the forefront of a nascent climate movement in medical education

A portrait of Cecilia Sorensen
Chantal Heijnen for STAT

When Cecilia Sorensen (above) was an emergency medicine resident practicing at Denver Health in Colorado a few years ago, summer was known as "trauma season." She realized there was a clear connection between patients' experiences and climate change. "How did I hear nothing, nothing, about this during my entire medical training?" Sorensen asked herself. Now, she's one of a growing number of committed young doctors and medical students across the country who aim to address that glaring oversight in their training, working to incorporate climate change into medical education.

The movement is still nascent, but it has already made an impact. In January, Harvard University's medical school committed to embedding climate and health in its curriculum. At George Washington University, students this year finally managed to get the school to adopt a "climate theme" that will weave learning objectives into all four years of medical school. STAT's Karen Pennar has more.


coronavirus

Fauci reflects on pandemic missteps, vaccine mistrust, and 'Monday-morning quarterbacking'

In a new interview with the New York Times, former National Institute of Allergy and Infectious Diseases head Anthony Fauci reflects on the way the U.S. initially responded to the pandemic, three years after the world-changing virus began to spread. While a production crew for a PBS documentary may dispute that it's his "most extensive interview yet," Fauci was candid about how he thinks about the early pandemic days with the benefit of hindsight during a chat that he called "serious Monday-morning quarterbacking."

On mistrust of science and vaccine mandates: "Man, I think, almost paradoxically, you had people who were on the fence about getting vaccinated thinking, why are they forcing me to do this? And that sometimes-beautiful independent streak in our country becomes counterproductive."

On if he should have emphasized more the urgent threat that Covid-19 posed when speaking to STAT's Helen Branswell in February 2020: "Yeah, I think, retrospectively, we certainly should have done that. ... We were not fully appreciative of the fact that we were dealing with a highly, highly transmissible virus that was clearly spread by ways that were unprecedented and unexperienced by us."

On what this pandemic can teach us about public health in the future: "I could say, well, hey, we tried our best, and we still got screwed, so we're going to get screwed no matter what happens in the next one. I don't think that's an appropriate response. I think we can still improve significantly."


patients

How transportation barriers affect cancer survivors' health

Adults who delay care due to a lack of transportation are more likely to use the emergency room and have a higher mortality risk compared to those with and without cancer who don't delay, according to a new study in the Journal of the National Cancer Institute. Cancer survivors facing transportation barriers are almost three times as likely to visit the emergency room and face more than twice the mortality risk as those without cancer history or transportation barriers.

By analyzing nationally representative survey data and mortality files, researchers found that 2.8% of cancer survivors and 1.7% of adults without a cancer history reported transportation barriers from 2000-2018, with direct implications for patient care. Cancer survivors are already at higher risk for comorbidities, meaning a lack of access to transportation can turn otherwise manageable conditions into emergency situations. More comprehensive solutions to transportation barriers are needed to ensure patients can receive timely care, according to the researchers. 


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What we're reading

  • An extreme risk of taking Ozempic: malnutrition, New York Times
  • Opinion: At-home clinical trials are the future, STAT
  • NIH rules are supposed to stop 'pass the harasser.' In one recent case, they appear to have failed, Science
  • Officials are trying to track down nurses with fake degrees from Fla. scheme, NPR
  • Morphic study shows promise — and blockbuster potential — for a pill to treat ulcerative colitis, STAT

Thanks for reading, more tomorrow! — Theresa

Theresa Gaffney is a reporter and podcast producer at STAT.


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