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As gene therapies fade, scientists look for solutions; WHO's Covid, mpox emergencies may be ending

May 4, 2023
Gene therapy helped Conner Curran (at right) walk, but as the drug fades, his family is supporting scientific efforts to allow him and other boys get a second dose.
Courtesy Jess & Chris Curran

STAT+ | Gene therapy has helped boys like Conner walk. Scientists are trying to keep it that way

Duchenne muscular dystrophy is being transformed by gene therapy. But success underscores a need to find ways to redose as the effects fade.

By Jason Mast


Covid and mpox are here to stay, but the WHO's emergencies may be nearing an end

Some global health experts say that while the diseases still pose threats, the time has come for the WHO to end its emergencies.

By Helen Branswell


Amid booming demand, Novo to hold back some doses of obesity drug Wegovy for new U.S. patients

The company said would temporarily limit some "starter" doses for new patients in the U.S. to ensure a supply for people already on the drug.

By Andrew Joseph



Researchers performed brain surgery on a fetus at 34 weeks and 2 days gestational age.
American Heart Association

In a first, a potentially fatal rare blood vessel disorder is treated in the womb

Since her birth, the infant hasn't needed drugs to treat heart failure, or postnatal surgery to treat the malformation, as is often the case.

By Ambar Castillo


STAT+ | Option Care takes over Amedisys in 'perplexing' $3.6 billion home care deal

Option Care Health is buying Amedisys, creating a national company that specializes in almost all types of home care.

By Bob Herman


STAT+ | NIH systems for non-human primate research fall short, threatening biomedical research

"Now is the time to strengthen the systems we need for nonhuman primate research," said Kenneth Ramos, whose NASEM committee issued the report.

By Ed Silverman


David Fajgenbaum of Every Cure presents at the 2023 STAT Breakthrough Summit.
Sarah Gonzalez for STAT

12,000 diseases lack treatments. One doctor thinks generics could yield cures

A doctor who saved his own life by turning to a generic is starting to use AI to search for other hidden cures in the pharmacopeia.

By Isabella Cueto


STAT+ | New Eli Lilly Alzheimer's data poses Medicare coverage conundrum

Eli Lilly's new data on its anti-amyloid Alzheimer's treatment ratchets up the pressure on Medicare's unprecedented restrictions on coverage.

By Rachel Cohrs


STAT+ | A new list ranks large pharmaceutical companies by research and development

Here's a look at the annual list produced by Idea Pharma and called the Pharmaceutical Innovation and Invention Index.

By Matthew Herper


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