Breaking News

Reanimating donor hearts, applying Covid lessons to forest fire smoke, & understanding plateauing BMI rates 

June 8, 2023
Reporter, Morning Rounds Writer
Good morning. Today we have a new method for heart transplantation, an "old" protection against a respiratory threat, and old and new trends in obesity rates.

Health

Reanimating hearts for transplant could expand available donor organs

Using machines to reanimate donor hearts after death for transplantation worked as well as traditional methods, the first large randomized trial comparing the two procedures concludes. In a new NEJM study, the survival rate of patients undergoing the new method was 94%, compared with 91% among patients who underwent the traditional method. The newer way could expand the donor pool by 30% in the U.S., the researchers project, if widely used. The study was funded by TransMedics, which makes the heart machine.

Traditionally, hearts have been removed from brain-dead donors and placed in cold storage for transport. In the new method, donations come after circulatory death from people on life support following major neurologic injury who don't meet the strict definition of brain death. But after the heart is removed, it goes into a machine that circulates blood through it, keeping it functioning through transport. STAT's Elaine Chen has more.


health

What wildfire smoke does to us — and Covid measures we can take

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Julie Jacobson/AP

Forest fires across Canada are sending unprecedented amounts of smoke pollution to regions of the eastern United States unaccustomed to such hazards, unlike people in cities like Beijing, New Delhi, and Santiago, Chile, where exposure is part of daily life. The danger comes from very fine particulates in the air, smaller than 2.5 microns in diameter and commonly abbreviated as PM2.5. STAT's Isabella Cueoto explains why low-income communities are hit harder, and tells us recent studies show that exposure to PM2.5 could make the body more susceptible to infections and neurodegenerative diseases.

What can people do now? For one thing, they can call on their experience with Covid-19, another threat to their respiratory health. STAT's J. Emory Parker tells us what's the same and what's different about masks and respirators (N95 vs. KN95), air cleaners, and ventilation for wildfire smoke. Read more.


politics

CDC comes under fire for Covid information lapses 

Outgoing CDC Director Rochelle Walensky submitted a plan in February to overhaul an agency blasted for its inadequate Covid communication. Republican lawmakers weren't impressed with the reorganization then or with the agency's response Tuesday to charges the proposals were charted behind closed doors. "We do need more information," Mary Denigan-Macauley, director of the Government Accountability Office's public health unit, told a House panel at a hearing yesterday.

Rep. Cathy McMorris-Rodgers (R-Wash.) said she had privacy concerns about a plan to require more data from state and local health departments. "​​CDC has broken the trust of the American people," she said at the hearing. But Rep. Frank Pallone (D-N.J.) pushed back: "I don't know how we can make improvements at the CDC when we fundamentally disagree on almost everything that happened during the crisis," he said. "We look at the same data and come to totally different conclusions about what to do." STAT's Sarah Owermohle has more.



Closer Look

BMI is starting to plateau — in richer countries

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Adobe, Alex Hogan/STAT

So there's modest good news about obesity. In high-income countries, rates are still rising, but they're not increasing as fast as they did on their way to 42% of the adult U.S. population. It's even beginning to level off, STAT contributor Julia Belluz reports. To understand how we got here, she looks back at what happened to make obesity rates triple since 1976. Ultra-processed foods get much of the blame, as does a more sedentary lifestyle. And while food is more available, we're not cooking at home as much as we used to. 

What's behind the slowdown in BMI growth in wealthier countries? Messages about obesity prevention may be getting through, Boyd Swinburn of the University of Auckland thinks. "Some countries are showing reductions amongst preschool children, especially from well-off households," he said. "So they're going to be the first group that come out of this epidemic and start to show decreases in prevalence." Read more.


obesity

Health equity leaders push for access to anti-obesity medications

As obesity rates still climb among Americans and more of them seek new weight-loss drugs, a new report cites deep disparities in who has obesity and who has access to comprehensive care for it, calling it an "access chasm." The Health Equity Coalition for Chronic Disease notes that Black adults have the highest prevalence of obesity (49.9%) compared with other racial groups, followed by Hispanic adults (45.6%), white adults (41.4%), and Asian adults (16.1%). Factors such as lack of access to healthy food or safe physical activity, both determined by lower income, put disadvantaged groups at higher risk.

The coalition, whose members include the NAACP and the National Hispanic Medical Association, call on CMS Administrator Chiquita Brooks-LaSure to expand Medicare coverage to anti-obesity medications and to improve access to intensive nutrition and behavioral counseling, as well as bariatric surgery. "The need for health equity is urgent," the group asserts.


mental health

For Chicago girls with PTSD, a high school counseling program helped

When researchers set out to test whether a high school-based counseling program could help young women in Chicago with PTSD, they had more eligible, interested applicants than their study, now out in Science Advances, needed. Their initial surveys found that although PTSD in girls often flies under the radar, 37% of the primarily Black or Hispanic 10th- and 11th-graders showed signs of PTSD, twice the prevalence of soldiers returning from Iraq and Afghanistan. The girls had experienced at least two traumatic events, including witnessing an attack (29%) and losing someone suddenly or violently (45%). 

The trial, conducted from 2017 to 2019, randomly assigned 3,749 students to participate in a group counseling and mentorship program or receive usual services weekly for four months. For program participants, PTSD symptom severity scores dropped 22% and moderate trauma-related distress fell 38%. Anxiety (9.77%) and depression (14.1%) also declined. The authors urge more help for this understudied population.


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What we're reading

  • Eisai-Biogen Alzheimer's drug data confirms benefits, FDA staff says, Reuters

  • A new system in California recasts gun violence as a public health concern. It's saving lives, The Guardian

  • Google strikes deal with Mayo Clinic to comb patient records using generative AI, STAT

  • Personal medical debt in Los Angeles County tops $2.6 billion, report finds, KFF Health News

  • After missing vaccine glory in pandemic, GSK looks to dominate other diseases, STAT

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