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Many sickle cell patients face impossible choice with new gene therapies

December 6, 2023
Molly Ferguson for STAT

New gene therapies confront many sickle cell patients with an impossible choice: a cure or fertility

The high risk of infertility will temper sickle cell patients' embrace of new gene therapy cures such as the CRISPR drug Casgevy.

By Megan Molteni


STAT+ | Using AI, scientists create blood test that measures organ aging and predicts disease risk

The findings suggest it might be possible one day to use a blood test to flag people at high risk for different organ-specific diseases.

By Megan Molteni


'Last roll of the dice' for a near-term HIV vaccine fails

A trial hailed as the last hope for an HIV vaccine this decade was shut down after a monitoring board found there was little chance of success.

By Jason Mast



Cydni Elledge/The New York Times

STAT+ | Opinion: A bold approach to pay for weight loss drugs for everyone who needs them

Medicare is facing disaster in the form of metabolic disease. New weight loss drugs like Wegovy can help, with a new approach to pricing.

By Jeremy L. Shane


Getting the lead out of the water supply: How one health expert crunched the numbers and prodded the EPA

An environmental health expert published a new cost-benefit analysis, and the EPA issued a more ambitious proposal to replace lead pipes.

By Annalisa Merelli


STAT+ | Using Pap smears for earlier ovarian cancer detection shows promise in small new study

New research used cells from routine Pap tests and found that detecting ovarian cancer as much as nine years before a diagnosis was possible.

By Elizabeth Cooney


Opinion: Listen: Rep. Raul Ruiz on going from the emergency room to Congress

Rep. Raul Ruiz discusses future pandemic preparedness, what politicians can learn from doctors, and more on the "First Opinion Podcast."

By Torie Bosch


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