Breaking News

A clue to unexplained toddler deaths, an experimental male contraceptive, & living with scoliosis 

January 5, 2024
Reporter, Morning Rounds Writer
Good morning. This is not the first time STAT's Eric Boodman has shared the painful stories of families whose babies have died from SIDS or SUDC, the term for unexpected deaths in children 1 or older. Read his latest on a possible new clue as to the cause.

neurology

A baby monitor captures a possible clue to sudden unexpected death in childrenSUDC_SIDS-18101-1600x900

André Chung for STAT

Hayden had a baby monitor in the room he shared with his twin, Cameron. This monitor was special, prompted by Hayden's febrile seizures. An otherwise thriving 17-month-old, he'd been convulsing after spiking high fevers, so the motion-detecting baby monitor was there, ready to trip an alarm. But it didn't, his father discovered one Sunday morning when he found Hayden lying still in his crib. 

The baby monitor did film what happened just before something known as Sudden Unexpected Death in Childhood. A study published in Neurology yesterday found that in a registry of 300 such deaths, seven of them were recorded, by baby monitors or "nanny cams" or security systems. In five of them, experts saw what looked like some kind of convulsion. It's not conclusive, but it's a start, said study co-author Orrin Devinsky. "I certainly have doubt. I wouldn't say I know 100% that it's seizures. But my goodness, it's extraordinarily strong evidence." STAT's Eric Boodman tells the story.


reproductive health tech

An injectable gel marks the latest experimental entry in male contraception

The search for male birth control that's more effective than condoms and less drastic than vasectomies is heating up. Spurred in the U.S. by women's waning reproductive rights, men are now more interested in protecting against unwanted pregnancy. "A lot of people are looking and thinking well, if we can't come at this from the women's perspective, maybe we need to come at this from the men's perspective and get more men involved in reproductive health," said Kevin Eisenfrats, CEO and co-founder of the device startup Contraline.

Contraline has built an injectable gel that is inserted into the sperm duct to block sperm. Yesterday it announced early results of a small trial in a press release along with its hopes to win FDA approval in 2027. STAT's Lizzy Lawrence explains how it works, and what other male contraceptives are also in development.


health tech

CDC takeaways on tuberculosis bone graft outbreak

When the CDC detected a tuberculosis outbreak last summer, there were two strange things about it, STAT's Lizzy Lawrence tells us. One, the disease spread through donor bone material unwittingly implanted by orthopedic and dental surgeons. Two, this unlikely event had already happened in 2021. Both outbreaks were linked to bone material from the company Aziyo Biologics.

In the CDC's latest weekly report, the agency reports what it learned after investigating the outbreak. On July 7 and 11, two separate health departments told the agency about patients developing strange infections and, based on the 2021 outbreak, suspected tuberculosis. The bone material tested negative according to a nucleic acid screening, possibly because of low TB concentration. But on a bacteria culture test, the gold standard of TB screening, the material turned up positive.

The moral of the story? Manufacturers should test their bone materials with cultures, the CDC recommends. Also, hospitals should warn patients about infectious disease risks before implantation and track the bone material post-implant.



closer look

Diagnosed with scoliosis, a dancer in high school advocated for her caremaddywelz

Photo illustration: Casey Shenery for STAT 

Being diagnosed with scoliosis at age 14 was a surprise to Maddy Welz, who learned she had a curve in her spine at a school screening. An orthopedic surgeon recommended she wear a back brace until she grew more, but in her first year of high school, the brace made her feel isolation, pain, and distance from her love of dance. She talked recently with STAT's Anika Nayak about what came next.

How did you push for spinal fusion surgery?

I started advocating for myself and amplifying that I was experiencing pain so my medical team could find a solution. My only two requirements [were] that it wouldn't interfere with my dance recital and plans to see Taylor Swift over the summer.

What does it feel like now?

I am currently five months post-op and still in some pain. Some days are better than others, where I am able to go to dance practice and perform, while others are painful and I have to lay in bed. I think I have come to terms with the fact that there will be things I can never do, especially in regards to dance techniques, but I am learning to cope as each day goes by.

Read the full interview.


cancer

Exercise should be part of the conversation during cancer screening, researchers suggest

Exercise can do a lot of good things, but its impact on cancer is complicated. A research letter in Cancer Cell looked at the Prostate, Lung, Colorectal, and Ovarian screening trial to see what exercise — from occasional to vigorous — meant for more than 60,000 people without a history of cancer. After following them for up to 20 years, they found that overall, exercisers had a lower risk than non-exercisers of some but not all cancers. 

Exercisers had a lower risk of head and neck cancer (26%), lung cancer (20%), and breast cancer (11%), but a higher risk of melanoma (20%) and prostate cancer (12%) compared to non-exercisers. Looking at mortality from any cause, exercisers not diagnosed with cancer had a 19% lower risk of death than non-exercisers. Exercisers who had cancer had a 17% lower risk of death from any cause. "From a clinical perspective, our findings raise the notion for exercise recommendations to be integrated into cancer screening visits," the authors conclude.


health

Using hearing aids linked to longer life and lower risk of dementia

Two studies in two days make a compelling case for people to wear hearing aids if they have hearing loss. The first, published Wednesday in the Lancet, found that people with impaired hearing who regularly wore their hearing aids had a 25% lower risk of dying over the study's 13 years. That association held up after accounting for age, income, race or ethnicity, education, and health, including how much hearing they had lost. The observational study couldn't show cause and effect, but it did make a case for getting tested and not assuming that hearing loss is an inevitable feature of aging. 

The second observational study, published yesterday in JAMA Otolaryngology — Head and Neck Surgery, suggests that hearing aids could lower the risk of dementia. People with hearing loss had a 7% higher chance of developing dementia over the study's 15 years, but that rose to 14% in those who didn't use hearing aids once diagnosed with hearing loss.


More around STAT
Check out more exclusive coverage with a STAT+ subscription
Read premium in-depth biotech, pharma, policy, and life science coverage and analysis with all of our STAT+ articles.

What we're reading

  • Doctors are as vulnerable to addiction as anyone. California grapples with a response, KFF Health News

  • The link between weight loss and work success, Wall Street Journal

  • Feng Zhang, Grail founder join forces on new gene editing startup, Moonwalk, STAT
  • Exclusive: Feng Zhang's year-old CRISPR delivery startup Aera lays off quarter of staff, STAT
  • The most mysterious cells in our bodies don't belong to us, The Atlantic

  • FDA is blasted by advocates for pursuing a deal with data provider that has ties to opioid makers, STAT

Thanks for reading! More on Monday,


Enjoying Morning Rounds? Tell us about your experience
Continue reading the latest health & science news with the STAT app
Download on the App Store or get it on Google Play
STAT
STAT, 1 Exchange Place, Boston, MA
©2024, All Rights Reserved.

No comments