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What to know about memory and aging in wake of Biden report

February 12, 2024
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Reporter & Podcast Producer

Good morning! Pfizer aired its first-ever Super Bowl ad last night celebrating its 175-year history, while Astellas promoted its menopause treatment Veozah. But next to all the other ads with celebrities like Jennifer Aniston and Jason Momoa, they may not have created quite the same buzz, which raises the question: Do you think pharma companies should shell out next year for a big name? Send your thoughts and creative ideas to theresa.gaffney@statnews.com.

health

A neuropsychologist's take on memory and aging in aftermath of Biden report

What is the relationship between aging, memory loss, and overall cognition? That's a matter of hot debate in the wake of special counsel Robert Hur's report on President Biden's alleged mishandling of classified documents. To understand more, STAT spoke with Joel Kramer, a professor of neuropsychology who directs the UCSF Memory and Aging Center:

Do memory lapses and losses in older age always indicate underlying conditions? Do they suggest other cognitive impairment, too?

When there's a considerable amount of disease, you might expect a more broad-based decline in memory as well as other [mental] skills. But they are really quite dissociable. And in fact, one of the ways that a lot of older people compensate for their memory problems is by having very good reasoning and planning and judgment. 

Read more.


first opinion

Opinion: King Charles doesn't owe us any information about his health

Last week, Buckingham Palace shared news that King Charles had started treatment for cancer.  And over the holidays, U.S. Secretary of Defense Lloyd Austin quietly went into the hospital for prostate cancer treatment without any sort of official statement or even communication to the White House. While it makes sense that a boss needs to know their employee is out of office, do WE — you and me, the peasants — have a right to know about any of it?

In a new First Opinion, professor and author Christina Beck argues that nobody — celebrity, public figure, or private citizen — should be forced to expand their privacy boundaries if they don't want to do so, especially regarding a health situation, even if "good" can come from it. Read more.


In the lab

Universities struggle to manage flood of research misconduct cases
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Adobe

Over the past decade, the number of research misconduct allegations reported to the National Institutes of Health has more than doubled, climbing from 74 in 2013 to 169 in 2022. And scientific sleuths are finding plenty of other problems that don't always qualify as outright misconduct.

Universities and scientific journals are struggling to play catch-up to assess whether alleged flaws are real ones, and, if so, what to do about it. But they're also trying to prevent problems from arising in the first place, by putting measures in place to catch errors before they're published and have proposed measures like imposing screening of all papers through AI image programs and ethics training for students and faculty. How strong are these solutions? Read more from STAT reporting duo Angus Chen and Jonathan Wosen to find out.


health

Women more likely than men to die from severe heart attacks

The number of women hospitalized for heart attacks between 2011 and 2018 declined at a greater rate compared to men, according to new research published in Circulation: Cardiovascular Quality and Outcomes that looked at data from six different high-income countries. And yet, in all six countries, women had higher mortality rates and were less likely to receive cardiac interventions like catheterization or treatment to restore blood flow to the heart. In 2018, women in the U.S. hospitalized for severe heart attacks had an 18.4% chance of dying within 90 days, compared to 17.1% for men.

The study, which looked at disparities of outcomes for older adults hospitalized for heart attacks in the U.S., Canada, England, the Netherlands, Israel and Taiwan, offers insights on the impact that sex can have on standards of care, as STAT's Deborah Balthazar explains. The study's authors say the higher mortality rates in women hospitalized for more severe heart attacks could be due to treatment delays or misdiagnosis — either because women present with different symptoms, or because medical professionals evaluate women differently from men.


research

How much focused thinking is the right amount for a concussed kid? 

Is your kid hoping to get to the Super Bowl someday? You may want to prepare to nurse them through a concussion or two along the way. Clinicians already understand that exercising earlier in the recovery process can help kids feel better faster, but it's still largely unclear when activities that require more attention or concentration should be re-introduced. 

A small new study, published in the British Journal of Sports Medicine, attempted to find out. Researchers at Nationwide Children's Hospital followed 83 adolescents with concussions through their recovery. Most recovered within a month, and they spent a daily average of over 3 hours doing low-intensity activities such as listening to music or texting, 2.75 hours on moderate ones like being in the classroom or at work, and 38 minutes on high-intensity activities like homework, tests, or giving a presentation. Throughout recovery, the more time participants spent on moderate or high intensity cognitive activities, the faster their concussion symptoms resolved. Researchers also found that each day a participant didn't return to school was associated with 8% slower symptom resolution.

But it's a tricky balance. While some moderate and intense cognitive activities may be helpful, engaging in such behavior too soon — especially if it involves a screen, like playing video games, in the first week — could make symptoms worse, researchers noted. Despite the association found in the study, it did not prove causality in either direction, so clinical trials are still needed to explore more, the authors wrote.


health care

FTC doubles down on case to limit private equity's physician buyouts

Last September, the FTC sued private equity firm Welsh, Carson, Anderson & Stowe and U.S. Anesthesia Partners, alleging the two parties conspired to create monopolies for anesthesia services. Both Welsh Carson and USAP have tried to get the case thrown out, but the FTC recently doubled down. The agency asked the judge last month to ignore those companies' pleas, calling their arguments "unavailing" in recent legal filings.

Experts say the agency's meticulous arguments and persistence to put Welsh Carson and USAP's business strategy on ice sends the clearest warning yet: Firms that try to consolidate markets for physician services as a means to jack up prices won't get away without a fight. "It's sending a political signal, at least in this administration, that the legal and regulatory risk of private equity in health care has heightened," Jane Zhu, a physician and professor at Oregon Health & Science University told STAT's Bob Herman. Read more.


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What we're reading

  • 'Fleeing under the cover of darkness': How Idaho's abortion ban is changing pregnancy in the state, CNN
  • What readers think about Aduhelm, CTE and the Super Bowl, and more, STAT
  • Social isolation takes a toll on a rising number of South Korea's young adults, NPR
  • Senators start work on Medicare physician payment reform, STAT
  • Lifesaving diarrhea cure for kids is underprescribed, researchers say, Washington Post

Thanks for reading! Until tomorrow — Theresa


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