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Prosthetic users might prefer tweezers to “natural” hands

June 11, 2024
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Morning Rounds Writer and Podcast Producer

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heart health

Two updates from the cardiovascular beat

Tim Boyle/Getty Images

STAT's Liz Cooney has been carving out the cardiovascular health beat, and yesterday she wrote about two new studies that are worth our time:

  • Statins may not be needed by millions of people: Last fall, the American Heart Association proposed a new risk calculator for heart disease. The model could mean far fewer Americans — as many as 40% less than current calculators say — would be candidates for cholesterol-lowering drugs, according to an analysis published yesterday. The old model, from 2013, was widely criticized as overestimating risk. Read more from Liz on what the future might look like.
  • Heat waves can put hearts into 'oxygen debt': When temperatures climb over 100 degrees Fahrenheit, heat can cause restricted blood flow and potential heart attacks, according to new research. About 60 participants in the experiment wore wetsuits, originally designed by NASA, that raised their internal temperatures. A third of the oldest, least healthy participants had blood flow blockages. They weren't in danger, the senior author told Liz, but there are grave implications for longer exposure to heat in the real world. Read more.

emergency department

New national data on emergency visits among homeless patients

CDC's National Center for Health Statistics released a new report today on visits to emergency departments, and how they compare between unhoused people and others across the U.S. Each year between 2016 and 2021, about 1.4 million unhoused people visited the ED, with women accounting for about a third of visits. Here are some quick takeaways from the report: 

  • Unhoused people who went to the ED were mostly middle-aged, between the ages of 26 and 64. Housed ED visitors, on the other hand, were typically either older or younger.
  • More unhoused people arrive at the hospital by ambulance (about 42%) compared to others (16%). 
  • For more than half of unhoused people in the ED, Medicaid was the primary payer for care; less than 5% had private insurance. Medicaid was still the top source of payment for others at 34%, but 25% had private insurance.

clinical trials

Medical device trials still don't enroll enough women 

Women have always been underrepresented in all types of medical studies. Some recent progress: Researchers recently analyzed more than 700 scientific journal articles from nine fields and found that in 2019, the number of studies that included women at all increased from 28% to 49%. But there's still plenty of room for improvement — a study published yesterday in JAMA Internal Medicine reveals that the percentage of women represented in high-risk medical device trials did not increase from 2010 to 2020. 

Women generally made up just 33% of participants when the study authors reviewed almost 200 trials from 2016 to 2022. But the percentages varied between devices: Women made up 46% of participants in orthopedic trials, but only 29% in cardiovascular studies. Read more in STAT+ from my colleague Lizzy Lawrence on the disparity in inclusion and why researchers think it has persisted. 



disability

Prosthetic users liked tweezers, wrenches as much as "natural" hands in a new study

 Courtesy Ottavia Maddaluno 

"Embodiment" is the ultimate goal for people who build prosthetic limbs. It's the feeling somebody gets when they have agency or ownership over a body part. For prosthetic users, it means more muscle control, improved sensory feedback, and less limb pain. But it's an elusive target — nearly half of people with upper limb prosthetics actually end up abandoning them. 

In a recent study, researchers took an unconventional approach to seek embodiment for users. Using virtual reality, participants tried out bionic tools like tweezers or wrenches instead of more "natural" hand prosthetics. And it worked: Participants felt as or even more embodied with these tools than with the "natural" option. The idea of "tool-mediated embodiment" isn't completely new to people with disabilities, STAT's Timmy Broderick reports, but it could expand the possibilities for prosthetics. Read more.


cancer

Are Gen Xers getting cancer more than previous generations?

Yes. That's according to a new study published yesterday in JAMA Network Open, in which researchers analyzed a cohort of 3.8 million cancer patients. Members of the lost generation born between 1965 and 1980 have experienced larger per-capita increases in rates of the leading cancers than any generation since 1908. Rates of thyroid, kidney, rectal, uterine, colon, pancreatic cancers and more have increased significantly between the Baby Boomer generation and Gen X, the study found.

The researchers were surprised by their own findings, they wrote. Science has identified preventable causes and screenings have become more standardized. But while some cancers, like those of the lung and cervix, have fallen, it's not enough to offset the rising rates of other cancers. If the trend continues among Millenials, the authors worry that cancer rates in the U.S. could "remain unacceptably high for decades to come," they wrote. To keep up on the latest news, read STAT's cancer coverage.


first opinion

A scientist calls for empathy regarding vaccine injuries

Kizzmekia S. Corbett-Helaire led NIH research that contributed to the technology in Covid-19 vaccines, so it makes sense that when she gives talks, people thank her for that important work. But there's one audience member that she'll never forget. Somebody approached her to say that a Covid-19 vaccine had harmed her, and to ask what Corbett-Helaire was doing to investigate vaccine injury. Corbett-Helaire gave a standard answer about the FDA and continuous monitoring. But in a new First Opinion essay, she asks herself: "Is that enough? Has my own science contributed to ignoring people who feel they have been harmed and not heard?"

Corbett-Helaire argues that people who speak out about how they feel after getting a vaccine should not be dismissed or assumed to be anti-vaxxers. Read more on how Corbett-Helaire believes that everyone, from researchers to regulators, can create a better system for understanding vaccine-related injuries.


More around STAT
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What we're reading

  • Bad math: NIH researchers didn't pocket $710 million in royalties during pandemic, Science

  • FDA advisers unanimously recommend approval of Eli Lilly's Alzheimer's disease treatment, STAT
  • Law enforcement unit is formed to crack down on illegal e-cigarettes, New York Times
  • Blood tests for cancer detection aren't yet ready for prime time, STAT

Thanks for reading! More tomorrow,


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