Breaking News

More and more Americans are dying avoidable deaths

March 25, 2025
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Morning Rounds Writer and Podcast Producer
Good morning! It was quite a rainy day in Boston yesterday — but at least it wasn't a cold one. I'm manifesting some sun for today.

politics

Trump picks a new CDC director

After the chaotic withdrawal of his first nominee to lead the CDC, President Trump has selected the agency's acting director, Susan Monarez, to take the role, STAT's Sarah Owermohle and Helen Branswell report. 

Monarez is a longtime biosecurity expert with ties to former President Biden's flagship health initiative, the Advanced Research Projects Agency for Health. If confirmed, she'll be the first CDC director since 1953 not to be a doctor of medicine. While she wasn't well-known before the news dropped yesterday, some that did know her apparently referred to her as "the Kevin Bacon of biomedical innovation." Read more.


public health

Does the kidney transplant system need to change?

A new study says yes — if the wait list for a kidney transplant were expanded to improve access, fundamental changes to the current model would be required to reduce or even maintain existing wait times. While there are about 90,000 people on the waitlist at any given time, per federal data from the fall, only about 25,000 kidney transplants take place each year. Adding 10% more patients to the waitlist would increase the average wait time by 4 months; adding 50% more patients would increase the time by almost two years. It would take an additional 2,800 kidneys to offset the 10% increase or 11,000 for a 50% increase, according to the analysis published yesterday in JAMA Network Open.

Right now, it's especially difficult for people with kidney failure (the most sick patients) to get on the wait list for a transplant, and once there, it takes them longer to actually get a new kidney. But it's not just the extreme cases that would benefit from more kidneys and shorter wait times — that could save lives across the board. Overall, large increases in kidneys from living donors are likely needed, as are research and policy initiatives that would promote it, the authors wrote. (They did not discuss xenotransplantation, which has received a lot of attention but is still in early days of research.)  


research

NIH removes outside advisers who evaluate research

Prominent outside scientists who help the NIH evaluate its internal research programs are being abruptly removed, according to five advisers whose positions were terminated and a recording of an internal meeting obtained by STAT's Megan Molteni and Jason Mast.

It's unclear why this is happening. The advisers who spoke to STAT were not given a reason, and have yet to receive an official notification of termination from the NIH. "I asked where this order came from and nobody seemed to know," one person said. Among those being terminated are people without U.S. citizenship, women, people from underrepresented racial and ethnic groups, and people who work in newly taboo areas like diversity and equity. Read more.



first opinion

How proposed budget cuts could affect dementia care

An older woman with grey hair sits in front of a window with her head down and hands folded. The room is in shadow but it's light outside.

Jae C. Hong/AP

Over the past 35 years, the U.S. has built up systems to support people living with dementia and their caregivers — often through programs that rely on Medicaid funding. But the proposed federal budget calls for $880 billion in cuts to Medicaid over 10 years. If that happens, these programs that rely on Medicaid will likely need to reduce their services or potentially close down. 

"People are afraid. I'm afraid. They are afraid of what will happen to them if they get this disease. They are even more afraid of how their families will cope," Hilda Pridgeon, a founder of the Alzheimer's Association, told Congress in 1990 while advocating for more support. In a new First Opinion essay, physician Jason Karlawish argues that this fear "will once again beset the American family" if the dramatic budget cuts are made. Read the essay, which includes the stories of two patients from Karlawish's memory clinic whose lives have been changed by Medicaid-funded programs.


global health

The world reduces avoidable deaths & the U.S. adds them, study says

In most high-income countries around the world, the number of avoidable deaths (avoidable thanks to preventative measures or treatments) has been decreasing over the past decade. But in the U.S., that number is increasing, according to a study published yesterday in JAMA Internal Medicine

Between 2009 and 2021, avoidable deaths in the U.S. increased from around 20 to 44 avoidable deaths per 100,000, the study found. The number of deaths increased in all 50 U.S. states, but the variation between each state also increased. Other countries saw about 14 fewer avoidable deaths per 100,000. In the European Union, the reduction was even greater, with an average of almost 24 fewer deaths per 100,000. 

The U.S. spends more on health care than every other high-income country, but the increase in avoidable deaths "suggests that there are concerning broad and systemic issues at play," the study authors write. They write that policy solutions promoting healthy food, limiting exposure to harmful products, addressing gun violence, and regulating motor vehicle safety are potential ways to address the multifaceted problem.


biotech

23andMe files for bankruptcy

Late on Sunday, the DNA-testing startup 23andMe said it will file for bankruptcy and CEO and co-founder Anne Wojcicki will depart, after she repeatedly tried and failed to take the storied but financially troubled company private, STAT's Jason Mast reported yesterday morning. The company will now try to sell itself through a court-supervised sale, and Wojcicki will continue trying to buy it. 

To understand how it all happened, STAT's Matthew Herper cites Ernest Hemingway's description of bankruptcy in the 1926 novel, "The Sun Also Rises": It happens "two ways: Gradually, and then suddenly." Bankruptcy is the worst outcome for both Wojcicki and the company's shareholders, Matt writes. But it's the customers that may suffer the most. Read more analysis in Matt's Take.


More around STAT
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What we're reading

  • Medical benchmarks and the myth of the universal patient, New Yorker

  • Impatient about cell and gene therapy? Progress in biotech is not always linear, STAT
  • A war within the war: Ukraine's ill children, New York Times
  • Health insurers' rapid adoption of AI tools is outpacing regulators' ability to keep watch, STAT

Thanks for reading! More tomorrow,


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