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Everyone's using these tests for cancer — but the data aren't there

June 4, 2025
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policy

The CDC chronic disease unit will fold, despite MAHA's focus

The HHS budget for 2026, released Friday, proposed $14 billion in discretionary funding for programs that aim to reverse the chronic disease epidemic. This makes sense, given the agency leadership's focus on eradicating chronic disease. But the budget also proposes abolishing the CDC's National Center for Chronic Disease Prevention and Health Promotion, instead folding it into the Administration for a Healthy America, a new entity that will also bring other centers under its umbrella.

But shifting work on chronic diseases to AHA may create more problems than it solves, Adriane Casalotti, chief of government and public affairs for the National Association of County and City Health Officials, told STAT's Liz Cooney. "That other agency does not exist right now," she said. "We don't really know where the programs would pop up again when, and who will do the work." Read more from Liz on what the budget says about the future of chronic disease prevention work.


reproductive health

CMS rescinds Biden's EMTALA guidance on pregnant patients 

Federal health officials have rescinded guidance issued by the Biden administration in 2022 that aimed to ensure hospitals in states with strict abortion bans would still provide appropriate emergency care like abortion to pregnant people if necessary. 

The Biden administration's guidance was issued weeks after the Supreme Court struck down the constitutional right to an abortion in the Dobbs case and, in a separate decision, dismissed a case focused on whether or not EMTALA — the federal legislation that establishes the right to emergency medical care regardless of one's ability to pay — includes emergency abortion care. Then-Secretary Xavier Becerra emphasized in a letter on the guidance that a clinician's legal and professional duty to provide such treatment should preempt any local restrictions. 

CMS said that it will continue to enforce EMTALA, and will work to "rectify any perceived legal confusion and instability" the guidance had created. But experts have long said that the source of confusion lies with state bans on abortions, which often offer vague criteria for which life-threatening emergencies may lead to an exemption. Read more from the AP


science

Researchers use continuous glucose monitors to link individual responses to metabolic states

With the number of people living with diabetes set to double in the coming decades, researchers are intensely interested in understanding why blood sugar levels can vary markedly after a meal between people eating the same food. A study published in Nature Medicine today offers new evidence that this person-to-person variation has to do with metabolic features that could inform personalized diabetes prevention and treatment plans.

A team led by Stanford researchers recruited 55 adults, nearly half of whom had prediabetes while most others had normal sugar levels, and had them wear continuous glucose monitors as they ate same-sized portions of meals delivered to their homes, with the foods including rice, bread, shredded potatoes, pasta, beans, grapes, and a mix of berries. The authors found that high glucose spikes after pasta were often linked to insulin resistance, a person's body not responding to the hormone, whereas participants with especially strong responses to potatoes included people who had beta cell dysfunction, meaning insulin-producing cells either struggled to produce the hormone or to release it.  Subjects with spikes after eating bread were more likely to have high blood pressure. The authors also found that an oft-recommended strategy of eating fat, protein, or fiber before a carb-rich food did blunt glucose levels, but only in people who were responsive to insulin. — Jonathan Wosen



cancer

Everyone's using these tests for cancer — but the data aren't there

Blood vials full of blood are twirling in the air against a white background.

Adobe 

Tests searching for tumor DNA in the blood are surging in popularity, mainly because they can clue clinicians into what's happening with a patient's cancer long before any changes appear on more traditional tools like MRI or CT scans. The tests can show if cancer patients will recur months before any lesions are visible, and some tests' results can give information about how a cancer will or is responding to a certain therapy.

It sounds good, right? These tests are commercially available and covered by Medicare. But there's one problem: Experts don't know if these tests actually help patients. STAT's Angus Chen spoke to cancer researchers about the technology, and all of them were enthusiastic about the technology's promise, but not ready to say these tests are useful in guiding better clinical decisions. 

"Research is trying to keep up with the pace of clinical use. It's a really exciting technology, but it's difficult to interpret and actually use test results," oncologist Stacey Cohen told Angus. Read more about how the hype might not match the research.


public health

How incarceration affects mortality — for people both inside and out

It's long been understood that incarceration has long-term effects on health and mortality. But a study controlling for both individual and area-level factors has new numbers on the connection. People who were incarcerated in 2008 had a 39% higher risk of dying and more than three times the risk of dying from an overdose by 2019 than people who weren't, according to the study, published yesterday in JAMA Network Open. And the risk of incarceration doesn't just affect the people inside — researchers also found that county incarceration rates were associated with increased all-cause mortality risks for nonincarcerated residents. (That increased risk for nonincarcerated people was not there when it came to overdose mortality.)

The results come from an analysis of more than 3.2 million people whose information from a 2008 Census interview was connected to mortality data through 2019. Most other studies are limited in that their control group is based on the general population, rather than people in the same area from the same dataset, the authors write. The results show how urgently improved health care during and after incarceration is needed, they add, specifically pointing to community-based primary care as a potential solution.

In related news on incarceration and health, a federal judge has ruled that the federal Bureau of Prisons must continue providing gender-affirming care including hormones and social accommodations to trans incarcerated people, blocking an executive order prohibiting such care. The AP has more. 


first opinion

America can't afford to lose international physicians

When the Trump administration put a pause on student visa interviews last week, thousands of J-1 physician visa holders poised to start their residency programs this summer were thrown into limbo. In a new First Opinion essay, orthopedic surgeon and former HHS secretary Tom Price argues that the country cannot afford to lose these doctors.

The government's own projections show that the U.S. will be short 124,000 physicians by 2027. The country has long benefited from attracting smart, medically-minded people from all over the world. Now, Congress needs to step up and create more flexible visa programs for international medical students to stay in America for work. Read more from Price about what this could look like.


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What we're reading

  • Cancer experts warn of coffee enemas and juice diets amid rise in misinformation, The Guardian

  • Opinion: HHS Secretary Kennedy told us not to listen to him. We agree, STAT
  • COVID vaccine changes confuse and upset some parents and families, NPR

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