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Trump, pharma drug price standoff continues

June 13, 2025
rose-b-avatar-teal
Disability in Health Care Reporting Fellow
I've been spending my time lately watching footage of the 7.9 earthquake that happened in Myanmar and Thailand in March. There's one video in particular in which the earth undulates like an ocean wave that's particularly unforgettable. This YouTube channel has innumerable videos from around the country depicting that same moment — from hotels to homes to hotpot restaurants.

SCIENCE

The fallacy of a systematic review

STAT/Adobe

Whenever I see a literature review for a topic I'm writing about, I often think, "Oh, great! I can trust this paper." Based on reporting from STAT's Anil Oza, I might need to reevaluate this impulse. A new JAMA Network Open paper adds to a body of evidence that not all systematic reviews are created equal and some researchers are trying out alternatives to these analyses. 

Systematic reviews, which involve pooling data from multiple studies and analyzing them together, are increasingly popular as a way to produce more authoritative conclusions than can be derived from the individual smaller papers. A small number of systematic reviews included retracted studies from paper mills, journals that produce low quality research to help researchers game the academic job market.

The problems are not limited to academia, either. In recent weeks, systematic reviews have been used to justify policy around gender affirming care as well as in the MAHA report. Media reports quickly followed in their wake showing that these reports were riddled with errors. Read more from Anil.


policy

More than 70 nutrition scientists call for freedom from censorship at NIH

Another day, another concerned public letter from scientists to National Institutes of Health director Jay Bhattacharya about the direction of the agency under his leadership. More than 70 top U.S. nutrition scientists signed a letter yesterday demanding that Bhattacharya address censorship at the agency, writing that their colleagues "need the freedom to present their findings in scientific meetings without political oversight, and to author and co-author freely in the scientific literature."

The letter is in part a response to censorship allegations from former NIH nutrition scientist Kevin Hall, whose groundbreaking research on ultra-processed foods was cut short when he quit in April, citing meddling from his superiors. Health secretary Robert F. Kennedy Jr. also recently threatened to bar NIH scientists from publishing in leading journals like JAMA and the Lancet "because they're all corrupt." The letter also asks for more investment in nutrition research at the agency, including doubling the current budget to $4 billion.

This follows Monday's letter from hundreds of NIH employees to Bhattacharya, which rebuked everything from the agency's cancellation of LGTQ+ research grants to the proposed cuts to support for indirect research costs at universities. In the words of my colleague Anil Oza: "Jay's inbox is FULL this week." Read the letter here. – Sarah Todd


standoff

Trump to pharma: lower drug prices *now*

The Trump administration is pushing pharmaceutical companies to voluntarily lower drug prices and allow companies to sell their drugs to Americans directly, but executives and industry lobbyists are antsy about taking the next step.

Lower priced drugs were a key part of Trump's presidential agenda, that Americans would pay no more than the lowest price for drugs paid by peer nations, but the administration's demands have been short on details since announcing the policy in May. The administration has not yet detailed how it would establish a direct-to-consumer mechanism, though it says that it has given companies price targets for their drugs: the lowest price offered in peer nations. 

It's the latest update in a weekslong saga that does not show any sign of ending soon. Will pharma companies voluntarily bend under the administration's scrutiny? Read more from STAT's Daniel Payne to find out. 



research

Work requirements would curtail Medicaid expansion coverage, report says

If the Senate passes the budget reconciliation bill, one in three adults who work or attend school while enrolled in Medicaid expansion coverage will be at risk of losing coverage under work requirements, according to new analysis from the Urban Institute and the Robert Wood Johnson Foundation.

Researchers say that among the 31% of enrollees in expanded Medicaid programs who do not work or attend school, only 2% of expansion enrollees do not work or attend school and cite lack of interest as a reason for not working. Instituting these work requirements would only actually affect a tiny fraction of the 4.8 to 6 million adults projected to lose coverage under the policy. This analysis is the latest report to demonstrate that Medicaid cuts could affect more Americans than Republicans suggest. 

Work requirements are important for Republicans who wish to reduce federal spending. The current provision would reduce federal spending by $280 billion over ten years, which amounts to nearly half of all estimated Medicaid savings in the bill, according to a Congressional Budget Office report. My colleague John Wilkerson's coverage has been excellent on this issue — stay tuned for more.


first opinion

Why RFK Jr.'s approach to the vaccine advisory committee could backfire

If Kennedy wants to "clean up the corruption and conflicts" at HHS, he is going about it the wrong way, writes Genevieve P. Kanter, an economist at the University of Southern California. 

Kanter studies conflicts of interest at federal agencies. She says that the purpose of advisory committees is to have external experts offer independent advice to the government on technical and scientific issues. Purging vaccine experts may remove members with industry ties, but not without a cost. Studies show that committee members with industry relationships tend to publish more and higher-impact articles, suggesting they can bring more expertise to the table. For more insight into why these existing relationships matter and why Kennedy's purge could backfire, read more from Kanter. 


More around STAT
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Read premium in-depth biotech, pharma, policy, and life science coverage and analysis with all of our STAT+ articles.

What we're reading

  • Shattered science: the research lost as Trump targets NIH funding, ProPublica
  • He's dying. She's pregnant., Washington Post
  • Tulane Scientist Resigns Citing University Censorship of Pollution and Racial Disparity Research, Associated Press
  • Medicare Advantage's supplemental benefits will cost taxpayers $86 billion this year, with little transparency, STAT
  • Colorado doctor fired by RFK Jr. from federal vaccine committee: "This decision is really going to undermine public trust," Colorado Sun

Thanks for reading! 
Rose

Timmy


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