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A perimenopause business boom offers hope, health, and hype

September 29, 2025
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Morning Rounds Writer and Reporter
Good morning. Outside of concerts, have you ever screamed at the top of your lungs with thousands of other people? Attendees at this year's AAP National Conference let one out the other day. Read on for some of the news that could have these pediatricians on edge. 

deadlines

Will the government shut down tomorrow?

If Congress doesn't fund the government by the end of the day tomorrow, patients across the country who have been receiving hospital-level care at home will be placed back in hospitals. The Acute Hospital Care at Home initiative —  typically renewed in government-funding bills — allows Medicare to waive certain rules so hospitals may provide inpatient hospital care in patients' homes. But CMS has sent guidance to participating hospitals stating that in the absence of Congressional action, "all inpatients must be discharged or returned to the hospital on September 30, 2025."

"All of a sudden you're talking about a huge influx of patients into the brick and mortar throughout the country," said David Levine, a physician at Mass General Brigham who leads a group of hospital at home program leaders. Read more from STAT's John Wilkerson and Mario Aguilar.


fact check

Answering burning questions re: MMR vaccines

On Friday, President Trump doubled down on calling for changes to the measles, mumps, and rubella vaccine. "BREAK UP THE MMR SHOT INTO THREE TOTALLY SEPARATE SHOTS (NOT MIXED!)," he wrote online. It's unclear where Trump initially got this idea, but to be clear: Parents are currently offered either the MMR vaccine or a one-shot combination of measles, mumps, rubella, and varicella (chickenpox) for their children, and there's little evidence that dividing the MMR vaccine up further would provide any health or safety benefit.

Read more from STAT's Anil Oza, who explains what we know about the shots, including when monovalent vaccines for measles, mumps, and rubella were phased out, what it would take to bring them back, and how separate shots might impact vaccination rates.


in these times

RSV vaccines are safe, per Cochrane review

Relatedly, some news that wouldn't necessarily be news in different times: Vaccines for RSV, a respiratory disease, are safe and effective at protecting the groups at highest risk of serious disease, such as older adults and babies, per a Cochrane review published today. The authors analyzed data from 14 randomized controlled trials including more than 113,000 participants, about 101,000 of whom were older adults. 

In June, health secretary Robert F. Kennedy Jr.'s handpicked Advisory Committee on Immunization Practices voted to recommend the use of a new monoclonal antibody against RSV in babies. This month, the committee raised doubts about vaccine safety and effectiveness data presented by CDC experts, floated a variety of theoretical or unsupported concerns of their own, and weighed a return to decades-old vaccine policy based on what they claimed were concerns from parents and patients, not public health needs or fresh data. And after President Trump made his strongest anti-vaccine comments yet last week, it's clear that Kennedy's influence is growing



reproductive health

A new women's health buzzword has entered the villa

An illustration of a page tearing off a calendar, the page itself illustrated with a female reproductive organ system. Behind that big calendar, a bunch of illustrated women stand, wrapped in their own reproductive calendars.

Molly Ferguson for STAT 

It's perimenopause — the period before the official onset of menopause that can last for years, characterized by fluctuating hormones. Menopause has been flooded with attention in recent years. (Everyone always thinks no one is talking about menopause, but these days everyone always is.) Now, hoping to expand on that $18 billion market, health entrepreneurs are coming for perimenopause with communities, supplements, meal plans, wearables, prescription medications, and more.

STAT's Sarah Todd spoke with women's health experts who say they're glad the topic is getting more attention, but they're also skeptical that all the new products can fix issues like sleep difficulties, hot flashes, mood swings, night sweats, brain fog, anxiety, hair loss, skin problems, weight gain, and low libido — many of which could be caused by perimenopause or by something else entirely. Read more from Sarah on the boom in perimenopause products, and the medical gap they're filling.


anniversaries

25 years of mifepristone

Mifepristone, commonly known as the "abortion pill," was approved by the FDA 25 years ago yesterday. At the time, "none of us working on expanding access to reproductive health care could have imagined the future we find ourselves in," writes Elisa Wells, a co-founder of the information resource Plan C Pills, which helps people in every state access abortion medication. In a new First Opinion essay, Wells celebrates the drug as "a hero in modern abortion access."

Read the anniversary essay, which comes just days after federal health officials initiated a new review to reassess the safety of the drug. But existing research demonstrates that the pill is safe and effective, even when delivered to someone's home.


first opinion

Introducing a new column on dementia

An estimated 7.2 million Americans are living with dementia, and that number could rise to as many as 13.8 million by 2060. In order to combat this growing problem, the way we talk about dementia needs to change completely. That's the argument made by physician and writer Jason Karlawish in his new column, called Neurotransmissions. 

We have to start talking more about the common diseases that cause dementia, Karlawish argues, including Alzheimer's, Lewy body, and newly discovered diseases like the oddly named LATE (limbic-predominant age-related TDP-43 encephalopathy). While LATE is little known even among physicians, it is perhaps one of the most common causes of dementia in people over 75. Read more and keep an eye out for future essays on the dramatically changing world of dementia.


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What we're reading

  • NIH pulled off a 'near miracle.' Scientists say there's still a problem, Washington Post

  • STAT readers on gun silencers as public health measure, 'lived experience,' and more, STAT
  • Anti-vax activists staged a rally exactly where an anti-vax gunman killed an officer last month, Mother Jones
  • Lilly executives: How the FDA's new PreCheck program can unleash the future of U.S. medicine manufacturing, STAT

Thanks for reading! More next time,


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