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What the evidence says about Tylenol, leucovorin, and autism

September 23, 2025
Illustration by Brendan Smialowski/Getty Images

What the evidence tells us about Tylenol, leucovorin, and autism

Trump highlights old but unsettled claims: Tylenol-pregnancy autism risk, leucovorin's promise of improved autistic speech. Here's what the science says.

By Matthew Herper


Countering Trump, European health officials stress that acetaminophen is safe to use during pregnancy

U.K. and E.U. regulators stress Tylenol is safe in pregnancy, countering Trump's claims that acetaminophen use could raise autism risk for children.

By Andrew Joseph


Trump, questioning vaccine safety, pushes major changes to how kids get shots

At a White House event on autism, Trump baselessly linked vaccines to the disorder and urged major changes in how kids get their shots.

By Daniel Payne, Anil Oza, and Chelsea Cirruzzo



Health and Human Services Secretary Robert F. Kennedy Jr. listened as President Trump spoke Monday at the White House.
Mark Schiefelbein/AP

In dispensing advice on Tylenol and autism, Trump takes on a new role: doctor in chief

Trump's Tylenol warning, more forceful than his Covid health claims, show a pattern of presidential medical advice at odds with science

By Jonathan Wosen and Angus Chen


STAT+ | Apple Watch's hypertension alert misses half of cases. Experts still think it will boost treatment

Experts say sensitivity rate may be low, just 41%, but that any feature that nudges people toward blood pressure care is a good thing.

By Mario Aguilar


Citing possible link to autism, Trump urges limiting use of Tylenol during pregnancy

Researchers say the science is inconclusive on both the risks of Tylenol and the possible benefits of leucovorin

By O. Rose Broderick


Alex Hogan/STAT

STAT+ | Scholar Rock SMA drug rejected due to problems at contract manufacturing site

The longstanding problems at the Indiana facility, which is owned by Novo Nordisk, have tripped up other drug approvals as well.

By Adam Feuerstein


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