Moderna forges ahead with cancer care, despite roadblocks

Also: Effort to guide treatment of cancer with novel blood tests may get boost from new research

October 24, 2025 Check out STAT+

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Bill Sikes/AP STAT+ | Despite a tough year, Moderna forges ahead with cancer therapies At ESMO 2025, Moderna's oncology chief explains the company's mRNA-4359 compound and why its cancer ambitions remain strong despite setbacks. By Andrew Joseph STAT+ | European oncology experts roll out guidance for use of large language models in clinical care  ESMO guidance designed to address opportunities and risks in patient-facing applications, AI tools for clinicians, standardized electronic health records. By Katherine MacPhail and Brittany Trang STAT+ | With questions surrounding its gastric cancer drug, Amgen fills in some gaps  Revised analysis of data on the drug, called bemarituzumab, had led to uncertainty about benefits, amid questions about possible safety issues as well. By Andrew Joseph STEVE GSCHMEISSNER / SCIENCE PHOTO LIBRARY STAT+ | Effort to guide treatment of cancer with novel blood tests may get boost from new research New data from Europe suggest Natera's Signatera ctDNA blood test can reveal which cancer patients need more therapy and who may already be cured. By Andrew Joseph STAT+ | Roche, Celcuity detail successful advanced breast cancer studies The two companies detailed their positive trials in advanced breast cancer, which could lead to new approvals, at the ESMO 2025 conference. By Andrew Joseph STAT+ | Enhertu pushes into early breast cancer, as antibody-drug conjugates move up the line Enhertu has powerful benefits for patients with breast cancer when given earlier in the disease, according to data presented at the ESMO Conference 2025. By Andrew Joseph

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In case you missed it "Cancer Doesn't Care": Citizen lobbyists unite to push past Washington's ugly politics, KFF. "When I was a child, everyone used it": women blame Johnson & Johnson talc for her cancer, the Guardian. This nation has the fastest rising rate of cancer cases — and deaths — in the world, NPR.

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