How Mark Cuban plans to ‘f— up’ health care

Plus, Mark's thoughts on Shark Tank and sports betting

November 21, 2025 Check out STAT+

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How much time does Mark Cuban spend thinking about health care? Why does he think TrumpRx, a direct drug purchasing platform that the Trump administration aims to launch, is "the most incredible program ever"? And what are his thoughts on sports betting? We discuss all that and more on this week's episode of "The Readout LOUD," STAT's weekly biotech podcast. Cuban comes on for an extensive chat about the latest biosimilar launch by his company, Cost Plus Drugs, as well his broader thoughts on the drug industry and how the direct-to-consumer field is changing. LISTEN NOW Subscribe to the podcast on Apple Podcasts or Spotify to never miss an episode Visit the archive to see past episodes

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