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Postscripts from the frontlines of 2025

December 11, 2025
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Morning Rounds Writer and Reporter
Good morning. Thanks to a post by writer and podcaster Aubrey Gordon, I learned yesterday about a striking photo series by artist Haley Morris-Cafiero called "Wait Watchers." In the photos, Morris-Cafiero, a fat woman, conducts what she calls "mundane performances," capturing the judgmental eye that others cast her way in public. 

hormones

FDA wants easier access to testosterone (for cis men)

A month after the FDA announced the removal of stringent warning labels for menopause hormone therapy, the agency hosted a panel to discuss testosterone, another hormone treatment with warnings attached. Earlier this year, the FDA removed a black box warning linking testosterone to increased risk of cardiovascular events. But warnings about a risk of prostate cancer persist, despite evidence to the contrary

Participants in the panel — which included urologists, HHS Assistant Secretary Adm. Brian Christine, and the CEO of a pharma company developing an oral testosterone therapy — largely supported the removal of that warning and rescheduling testosterone to a lower drug classification. Read more from STAT's Annalisa Merelli about their reasoning and how the discussion went.


medicine

Fewer hospitals are capable of treating kids

In the past twenty years, the number of hospitals that are capable of treating kids and adolescents has dropped significantly, according to a study published yesterday in Pediatrics. Meanwhile, the number of hospitals providing virtually no pediatric care outside of the ER or obstetrics more than doubled. 

The results come from an analysis of nearly 4,000 hospitals between 2003 and 2022. Each institution was rated from level one through four, with level one indicating the most robust pediatric capabilities and level four the least. Over the time frame, level one hospitals decreased by 38%, level two by 54%, and level three by 48%. Even level two and three services (like appendectomies or hospitalization for pneumonia or asthma) typically require a pediatric inpatient unit, which many hospitals have closed, the authors write. They pointed to lower Medicaid reimbursement levels and a shortage of pediatric providers as contributing factors in the decline.


research

What causes myocarditis?

Extensive studies have found Covid-19 vaccines to be safe and effective, having saved millions of lives during the pandemic. But these shots do come with a rare risk of inflamed heart muscle, or myocarditis. In a study published yesterday in Science Translational Medicine, scientists identified a pair of immune signals they believe drive these cases — and offered early evidence that the signals can be blocked.

"I want to emphasize this is very, very rare," said senior author Joe Wu. "People talk about it, and here we provide a mechanism." Read more from STAT's Jonathan Wosen on the science.



special repor

A collage of abstract human torsoes and figures , along with black and white medical imagery

Laura Weiler for STAT

Over the year, STAT reporters have interviewed scientists, patients, university administrators, and federal health workers whose lives have been disrupted by the Trump administration's seismic changes to America's science infrastructure. In the latest installment of our series, reporters caught up with some sources to hear how they've been since we last heard from them. Postscripts include:

  • Karen Hollit, a former FDA employee who lost her job on April 1. STAT's Eric Boodman first spoke to Karen this spring about how, even before the layoffs, the Trump administration had triggered her PTSD from her time in the Air Force. 
  • Josh Fessel, a former NIH employee who resigned "on moral grounds" in February. Working at the federal agency was his dream job. STAT's Anil Oza caught up with Josh to see if he was able to find a new position.

And more. Read their stories.


public health

(Don't) talk to your budtender about whether weed while pregnant is right for you

Medical organizations advise against using weed when pregnant. And yet even as tobacco use among pregnant people declines, weed use has increased over the years. In a secret shopper study published yesterday in JAMA Network Open, California shoppers spoke on the phone with more than 500 "budtenders," retail workers at state-licensed cannabis shops.

In answering the shoppers' questions, less than 1% of budtenders claimed that smoking a blunt (weed in a cigar wrapper) or using tobacco while pregnant is safe, but 20% said using weed was. Most (79%) said tobacco and blunts were unsafe, while about 40% said using weed was unsafe. Under half (44%) of the employees recommended speaking to a doctor before being prompted by the caller. 

To be clear: Prenatal cannabis use is associated with adverse outcomes for mothers and their babies, including gestational hypertension for the parent and low birthweight or neurodevelopmental problems for the children. This year (after the study ended), a California law went into effect requiring retailers to prominently display a brochure on the health risks of weed either at the point of sale or upon delivery. In addition, mandatory budtender education on those risks is needed, the study authors write.


first opinion

When to launch an mpox vaccine booster trial

In a new First Opinion essay, two scientists argue that the time is now. In New York, Chicago, and Los Angeles, cases are once again on the rise. And even though the numbers remain far below the levels seen during 2022, the authors — queer people who worked on the response to that epidemic — are already receiving questions from their local communities about the likelihood of another emergency situation. One question comes up consistently from other queer people: When should I get an mpox vaccine booster?

But as they write in the essay, they're currently unable to give a satisfying answer. Research is both limited and slow. Read more on the most urgent questions and the barriers that might stand in the way.


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What we're reading

  • This HIV expert refused to censor data, then quit the CDC, KFF Health News

  • Top HHS official evades discussing Trump plan to block state AI laws, STAT
  • ICE is using smartwatches to track pregnant women, even during labor, The Guardian
  • Sperm donor with rare cancer-causing mutation fathers nearly 200 children across Europe, STAT
  • House Democrat seeks to impeach Kennedy for undercutting public health, New York Times

Thanks for reading! More next time,


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