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The top medical advances of 2025 

December 31, 2025
KJ Muldoon with his parents, Nicole and Kyle Muldoon, at the STAT Summit in Boston in October.
Jeff Pinette for STAT

The top medical advances of 2025

New drugs reshaped care for HIV, obesity, lung cancer, and more in 2025. Prepare to hear more about drugs such as Yeztugo, Nuzolvence, Tagrisso and Enhertu.

By Matthew Herper


NIH begins review of thousands of delayed research proposals, funding 135 on first day

Hundreds of delayed research proposals earn a review on their merits, but still must survive NIH review for alignment with Trump priorities

By Anil Oza


Opinion: The most-read First Opinion essays of 2025

In 2025, STAT readers devoured op-eds on vaccines, MAHA, AI, health insurance, and other crucial topics.

By Torie Bosch



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