The U.S. vaccine schedule's biggest changes in decades

Also: How one urologist challenged medical assumptions about testosterone — and changed how men's health is treated

December 23, 2025 Check out STAT+

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RONALDO SCHEMIDT/AFP via Getty Images Trump administration's plan to shrink vaccine schedule sends health sector scrambling The health sector is working to navigate what could be the most significant changes to the U.S. vaccine program in decades. By Daniel Payne, Chelsea Cirruzzo, and Helen Branswell FDA approves pill version of Novo Nordisk's Wegovy, possibly widening access The oral version of the obesity therapy led to similar efficacy as the injectable weight loss treatment in a late-stage clinical trial. By Elaine Chen STAT+ | How the Trump administration is recasting government's role in regulating health technology Trump's health agencies are accelerating AI and digital health adoption while dismantling guardrails, raising questions of safety, oversight, innovation. By Casey Ross, Mario Aguilar, Katie Palmer, and Brittany Trang Carolyn Kaster/AP How testosterone fell out of favor in medicine — and how it came back For decades, doctors believed testosterone caused prostate cancer. One urologist challenged that dogma — and changed how men's health is treated. By Annalisa Merelli STAT+ | Trump administration to scrap federal rule requiring transparency into health AI tools  The Trump administration wants to scrap rules that require developers to disclose how AI tools to treat patients were developed and tested. By Casey Ross Opinion: 4 questions to understand the costs of 'medical freedom' Four questions all policymakers, regardless of whether they are supportive of vaccines or not, must consider when changing vaccine requirements. By Sarah Despres Kevin Frayer/Getty Images STAT+ | Opinion: China biotech's Cambrian explosion The sheer energy of China's biomedical ecosystem is producing something that looks like evolution on fast-forward. By Brian Finrow

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