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Jeffrey Epstein’s tissue sample ignited a furor in George Church's lab in 2013

February 24, 2026
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How Jeffrey Epstein's tissue sample ignited a furor in a Harvard Lab

epstein-1600x900Camille MacMillin/STAT; Photo: Jon Elswick/AP

In 2013, when Jeffrey Epstein wanted his genome sequenced, he knew exactly who to ask. Renowned geneticist George Church's connections to Epstein go back more than two decades, and have been public for years. But today, STAT's Megan Molteni reports new details about a furor that was ignited in Church's lab over a request to prioritize the sequencing of Epstein's sample over others that had been in the queue much longer. Mad Ball, the director of research at the time, wanted to quit on the spot when they realized what was going on.

"It was such a shock to me I didn't even have words," Ball said to Megan, who interviewed lab members and obtained emails about the incident. Read the story for the details, and how other participants in the genomics program have reacted to the news.

And if you're wondering: Nobody seems to know where Epstein's sample went. Megan followed the paper trail for answers.


turnover

No. 2 CDC official abruptly steps down

Ralph Abraham abruptly resigned from his role as the CDC's deputy director yesterday, STAT's Helen Branswell reported. A statement posted to the agency's website cited "unforeseen family obligations."

Abraham, a former Louisiana surgeon general who may or may not be a board-certified family physician, was sworn in only 2 1/2 months ago. That's just over six Scaramuccis, as one STAT editor noted. Read more from Helen.


immunity

Hepatitis B vax rates are dropping

After a period of growth, the percentage of newborns being vaccinated against hepatitis B has seen significant declines in the last couple years, a study published yesterday in JAMA found. Around the country, vaccination rates rose from 67.5% of newborns in 2017 to a peak of 83.5% in February 2023, before declining to 73.2% in August 2025.

To arrive at these numbers, researchers analyzed data from thousands of hospitals and clinics that use Epic's electronic health records system. While acknowledging that correlation is not causation, the authors note that the decline in vaccinations corresponded with "a period of heightened public discourse" about vaccination in the wake of the Covid-19 pandemic, including interviews with Robert F. Kennedy Jr. on Joe Rogan's podcast and Fox News.

These declines are likely to continue, as the CDC's Advisory Committee on Immunization Practices voted in December to recommend delaying when most babies begin to be vaccinated against the virus. Experts told Helen that, for some families, there could be considerable ramifications to that decision. And as a reminder, STAT's Eric Boodman wrote in September about the history of the CDC's longstanding recommendation for universal vaccination at birth.



health tech

Here's the deal with 'digital twins'

A futuristic looking "scan" of a human body, outlined in blue neon with circles surrounding the body. On either side of the body are more futuristic "screen" esque displays with data, presumably about the body.

Adobe

It's an ambitious goal: personalized health predictions based on a virtual model, or "digital twin." Want to know how a patient will respond to a certain drug or surgery? Uncertain when another might need a knee replacement? Imagine if all a doctor had to do was "treat" the patient's "twin" to find the answer.

Industries like aerospace and auto manufacturing have been able to widely adopt such predictions. Health care, on the other hand, has lagged behind. "When you start to throw humans into it … it's not as nicely deterministic," said Michael Grieves, who's credited with originating the idea in hardware manufacturing about two decades ago.

Read more from STAT contributor Mohana Ravindranath about what piecemeal implementation in health care has looked like so far and what the future might hold.


one small number

30%

While several drugs can be used to address inflammatory bowel disease, only about 30% of people living with the condition find relief. But as STAT's Allison DeAngelis reports, a new wave of treatments are being studied to address the chronic autoimmune condition. And here's one corresponding big number: AbbVie, Eli Lilly, Pfizer, and Merck have spent a combined $30 billion over the last few years acquiring startups with drug candidates that target unexplored avenues of inflammation. Read more from Allison on what's coming down the pipe.


first opinion

A new era of advocacy for physicians

The voice of a physician has always carried weight, especially when it comes to advocacy for public policies. In a new First Opinion essay, Sarah C. Nosal, the president of the American Academy of Family Physicians, argues that it's more important than ever for doctors to leverage their authority to push for a variety of changes that shape care both inside and beyond the exam room.

Advocacy isn't easy, Nosal acknowledges. It can take up time that doctors don't have and provoke public criticism. Still, "physician advocacy must stop being so quiet," she argues. "It needs to be a roar." Read more on how doctors can find their voice.


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What we're reading

  • Pausing puberty blockers trial seems political, not scientific, says Cass, Observer

  • FDA unveils rules for bespoke gene therapies, predicting flood of rare disease applications, STAT
  • Leah Stavenhagen, advocate for young women with ALS, dies at 33, New York Times
  • Bayer sues J&J over 'false and misleading claims' about competing prostate cancer treatments, STAT

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