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What an abortion clinic asks of patients, engineering bird flu resistance in chickens, & how Nick Jonas manages his type 1 diabetes

October 11, 2023
Reporter, Morning Rounds Writer
Good morning. The reproductive justice movement is often loath to criticize its own, STAT reporter Eric Boodman notes in his story today. But in one case, former employees did speak out. Read what they said, and the response.

reproductive health

The 'abortion queen' wants patients to have 'skin in the game.' Is that restricting access?

Diane Derzis, owner of the Jackson Women's Health Organization clinic in Jackson, Miss., pauses as she gathers her thoughts at a news conference on her reaction to the U.S. Supreme Court overturning Roe v. Wade, Friday, June 24, 2022.

Rogelio V. Solis/AP

Stephanie Rosenwinge was excited to work for the "abortion queen," Diane Derzis (above), who owned the clinic at the center of the Dobbs decision. Rosenwinge had firsthand experience with the importance of abortion care, and she thought of her new boss as a hero. But she was alarmed, she said, when Derzis instructed staff to make sure that patients were paying at least something out of pocket, even if abortion funds had agreed to cover that person's entire bill. Other former employees shared Rosenwinge's concerns.

Derzis told STAT that this directive was a way of making sure that limited funds were being used wisely. There was also a cash flow issue, she went on, explaining that abortion funds are often months late in sending large sums — and she needs that money to pay staff and rent. In this disagreement lies a broader question: How to ethically provide care in a crisis? STAT's Eric Boodman has more.


hospitals

Dana-Farber CEO: The need for a cancer hospital explains Mass General Brigham split

It was a bombshell for the Boston hospital community last month when Dana-Farber Cancer Institute announced it was dropping its longstanding partnership with Mass General Brigham in order to build a new cancer hospital with another Longwood neighbor, Beth Israel Deaconess Medical Center. MGB's CEO Anne Klibanski has since said she was blindsided by Dana-Farber's announcement, noting that the parties were in the process of negotiating an extension to their contract. 

Dana-Farber CEO Laurie Glimcher calls that a "false narrative." Yesterday she said building a freestanding cancer center has long been her primary goal, a mission shared by at least five other cancer centers.  "It would have been easier if MGB would have said, 'Yes, we can do that with you,'" Glimcher told The Boston Globe's editorial board. "That would have been the easiest path. But they refused over and over and over again." STAT's Tara Bannow has more.


infectious disease

To engineer bird flu resistance, chickens get CRISPR'd

roosterLeon Neal/Getty Images

Humanity has long fiddled with the traits of the crops and animals raised for our food. Now scientists are editing the genomes of chickens with another goal: to thwart the particularly pathogenic strains of bird flu virus that have been sweeping through nearly every corner of the globe. The virus has decimated both wild and farmed birds — and tipped into mammals as well.

In a paper published yesterday in Nature Communications, U.K. researchers explain how they used the gene-editing tool CRISPR to change a protein in chicken cells that flu hijacks to make copies of itself. If the virus can't take over that protein, the thinking goes, it can't establish an infection. It worked: Nearly all the chickens with genomes edited to resist the flu did so, even when exposed to high doses. It's a proof-of-concept experiment now, with more research needed. STAT's Andrew Joseph explores the questions that remain.



Closer Look

'It's going to be OK': How Nick Jonas handles his diabetes

nick jonas

Courtesy HLTH

You may know Nick Jonas (above) as one-third of the illustrious Jonas Brothers band. You may not know he lives with type 1 diabetes and is a celebrity spokesperson for Dexcom, maker of the continuous glucose monitor he wears. He recently talked with STAT's Nicholas St. Fleur at HLTH in Las Vegas.

Have there been times when you wish you didn't have this disease?

Absolutely. Before I had the technology that we have today, it was 12 or 14 finger sticks, as well as injections and other things while going through major hormonal changes during puberty. I was going on tour in front of thousands of people while also trying to be a spokesperson for a disease that is incredibly challenging and not predictable, for sure.

What did you decide when you were diagnosed at age 13?

I'm going to try to normalize speaking about diabetes. When I was scared sitting in a hospital learning about what my new reality was, there wasn't a person on a platform that I could point to and say, it's going to be OK. 

Read the full interview.


health

After abnormal cancer screening results, more than an EHR reminder brought more patients back in

For preventive cancer screening to work, patients must come back if those tests show abnormal results. A new study in JAMA analyzed what approaches worked best to bring overdue patients back to their primary care doctors  — who ordered the tests — within four months of receiving abnormal results. Among nearly 12,000 patients, a combination of electronic health record reminders, letters, and phone calls were more successful than EHR reminders alone in bringing patients back in after abnormal results for breast, cervical, colorectal, and lung cancer.

Still, the more intensive strategies worked for only about 31% of patients, which was better than the 21% of patients who got only EHR reminders. "Patient factors may include need for education about the meaning of the test results, what follow-up procedures involve, and assessing patient preferences," the authors write. "Practitioner factors such as knowledge of guidelines and improved access to prior test results may also be important."


health equity

Chronic kidney disease tied to elevated risk of sudden cardiac arrest in Hispanic and Latino adults

Sudden cardiac arrest — when the heart abruptly stops beating — has a terrible fatality rate of 90% among the 350,000 Americans it strikes each year. Predicting who's vulnerable isn't as easy as pointing to heart disease. A new study in the Journal of the American Heart Association reports that chronic kidney disease was the strongest risk factor for sudden cardiac arrest among Hispanic or Latino adults. In the first study to evaluate this population for risk factors, the researchers found that half of the sudden cardiac arrests occurred in people diagnosed with chronic kidney disease, 20% of whom had end-stage disease requiring dialysis.

Previous research studies have suggested that the progression of chronic kidney disease to complete kidney failure occurs rapidly among Hispanics and Latinos. This may be come from lower access to care, including dietary counseling, dialysis, and kidney transplantation, among this population, study co-author Sumeet Chugh told STAT's Anika Nayak. Read more.


In this week's First Opinion Podcast, First Opinion editor Torie Bosch speaks with endocrinologist Jody Dushay and cancer patient Laurie Brunner about the logistical and medical problems that the ongoing shortages of GLP-1 medications are creating. Listen here.


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What we're reading

  • A fraught question for the children of Alzheimer's: Is it coming for us? Boston Globe
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  • Akero's treatment for NASH falls short in cirrhosis study, STAT

  • Walgreens pharmacy staff walk out, citing unsafe working conditions, Washington Post

  • Opinion: How good are AI health technologies? We have no idea, STAT

Thanks for reading! More tomorrow,


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