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An international moratorium on genetically modified babies

May 14, 2025
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science

Let's revisit genetically modified babies in a decade, scientists say

A close up shot of a hand in the dark, placed on the rim of a round, glass device. (An embryologist who was part of the team working with scientist He Jiankui adjusts a microplate containing embryos at a lab in Shenzhen in southern China in 2018.)

Mark Schiefelbein/AP

Leading trade organizations representing the makers of cell and gene therapies are calling for a 10-year international moratorium on the use of CRISPR and other DNA-editing tools to create genetically modified children, STAT's Megan Molteni reported yesterday. The move comes more than seven years after Chinese researcher He Jiankui announced the birth of the world's first CRISPR babies.

The statement has no legal or regulatory force, but is intended to signal that attempts to alter the genomes of eggs, sperm, or embryos destined for live births remain unacceptable at this time. Read more from Megan on what it means.


politics

RFK Jr. arrives on Capitol Hill

On the same day that health secretary Robert F. Kennedy made major, unprecedented cuts to the federal health workforce, senate health committee Chair Bill Cassidy (R-La.) and ranking member Bernie Sanders (I-Vt.) asked him to appear before the committee. It's been over a month since that ask was made, but today, Kennedy will appear before lawmakers. In the morning, he'll face the House Appropriations committee, and in the afternoon, Cassidy's HELP committee. At both meetings, Kennedy will be asked about the Trump administration's budget request which, if approved, will cut funding to HHS by nearly a quarter from its current levels.

Cassidy plans to ask Kennedy to address worries that the overhaul across HHS is impeding its critical duties, according to excerpts of his prepared remarks that STAT's Daniel Payne has reviewed. He supports reform at the agency — saying "bureaucratic bloat and regulatory hurdles" are impeding the agency's core work — but will also push for Congress to be included in any plans. Read more from Daniel about what Cassidy and other senators are focused on, and keep an eye out for more coverage from STAT later today.



policy

It may soon be even harder to get mental health care

When Congress passed the Mental Health Parity and Addiction Equity Act of 2008, the law was supposed to prevent private insurance companies from instituting unequal coverage for mental health and physical health services. But multiple federal reports indicated that the law fell short, as insurance companies routinely exploited loopholes to avoid paying commensurate rates for mental health services.

In 2024, the Biden administration attempted to close those loopholes. Now, the Trump administration seems to be walking back the updates. "I'm not surprised, but I'm disheartened," Deborah Steinberg, a senior health policy attorney at the Legal Action Center, told STAT's O. Rose Broderick. Read more from Rose about the details and what it means for the future of mental health care in the U.S.


courts

'I don't know that': Federal judge flags factual claims in NIH grant termination case

The Trump administration's termination of hundreds of research grants has triggered swift legal responses, including a lawsuit filed by 16 state attorneys general. During a Tuesday hearing in U.S. District Court in Massachusetts, Judge William Young took a moment to read through a couple of grant termination letters. Young paused often while reading, remarking "I don't know that" after reading assertions that research based on gender identity is often unscientific, ignores biological reality, has little return on investment, and does nothing to enhance the health of Americans. He made similar comments while reading through a letter claiming that diversity, equity, and inclusion studies often support unlawful discrimination based on race and other characteristics.

"At least my understanding of medical research, and I stand to be corrected, is that it should take account of race and gender. Sickle cell anemia is more prevalent in a particular race. A certain type of cancer affects Ashkenazi Jews more than other people," Young said.

If there's no factual basis for these statements, he added, then it's possible the court could rule the terminations violated federal law because they were arbitrary and capricious. But that remains to be seen. Tuesday's hearing was a procedural hearing to set the schedule for future appearances by lawyers representing both sides in the case. — Jonathan Wosen 


first opinion

Can dying people really will their body to live?

Earlier this spring, Pope Francis was so sick with pneumonia that he was hospitalized for more than five weeks. He recovered just long enough to return to the Vatican for one last Easter Sunday Mass. He died the following day, from complications related to a stroke. It's the latest example of a certain, powerful account of a person seemingly postponing their own death for the sake of living one more important day.

This isn't just the stuff of fables. As infectious disease physician Arjun Sharma explains in a new First Opinion essay, researchers have investigated this phenomenon before. Still, it's far from settled science. Read more in Sharma's essay on what could compel a person to survive.


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What we're reading

  • A different way to think about medicine's most stubborn enigma, The Atlantic

  • Trump wants Europe to pay up for drugs to help lower prices for Americans. It won't be easy, STAT
  • Trump administration announces $450 million in new Harvard funding cuts, Boston Globe
  • State AI laws would be banned under clause buried in House budget bill, STAT

Thanks for reading! More tomorrow,


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